293 models ranked for pharmaceutical and life sciences. Scored with bonuses for reasoning (research analysis), large context (papers/patents), JSON mode (structured data), web search (literature), and function calling.
| # | Model | Score |
|---|---|---|
| 1 | GPT-5.4 ProOpenAI | 91 |
| 2 | GPT-5.2 ProOpenAI | 90 |
| 3 | GPT-5 ProOpenAI | 90 |
| 4 | o3 ProOpenAI | 82 |
| 5 | Claude Opus 4.1Anthropic | 81 |
| 6 | o3 Deep ResearchOpenAI | 74 |
| 7 | o1-proOpenAI | 77 |
| 8 | Claude Opus 4.6Anthropic | 71 |
| 9 | Claude Opus 4Anthropic | 76 |
| 10 | Claude Opus 4.5Anthropic | 70 |
| 11 | GPT-5.4OpenAI | 70 |
| 12 | Claude Sonnet 4.5Anthropic | 69 |
| 13 | Qwen3 VL 30B A3B ThinkingAlibaba | 69 |
| 14 | Qwen3 VL 235B A22B ThinkingAlibaba | 69 |
| 15 | GPT-5.2OpenAI | 68 |
| 16 | Claude Sonnet 4.6Anthropic | 68 |
| 17 | GPT-5.1OpenAI | 67 |
| 18 | GPT-5.3-CodexOpenAI | 67 |
| 19 | GPT-5.2-CodexOpenAI | 67 |
| 20 | GPT-5OpenAI | 67 |
| 21 | o4 Mini Deep ResearchOpenAI | 66 |
| 22 | GPT-5.1-Codex-MaxOpenAI | 66 |
| 23 | Gemini 3.1 Pro Preview Custom ToolsGoogle | 68 |
| 24 | Gemini 3.1 Pro PreviewGoogle | 68 |
| 25 | Gemini 3 Pro PreviewGoogle | 68 |
| 26 | GPT-5 MiniOpenAI | 65 |
| 27 | GPT-5 NanoOpenAI | 64 |
| 28 | Grok 4.1 FastxAI | 64 |
| 29 | Grok 4 FastxAI | 64 |
| 30 | Claude Haiku 4.5Anthropic | 63 |
Analyze molecular structures, predict drug-target interactions, and generate candidate compounds. Reasoning models evaluate pharmacokinetic properties and safety profiles.
Process trial data, generate statistical summaries, and identify adverse events. Large context handles full study protocols and regulatory submissions.
Search and synthesize scientific publications, patents, and clinical guidelines. Web search models access the latest research for up-to-date evidence summaries.
Draft IND applications, NDA sections, and compliance documents. JSON mode produces structured data for eCTD submissions and FDA databases.